INCREASED ZINC AND MANGANESE IN PARALLEL WITH NEURODEGENERATION, SYNAPTIC PROTEIN CHANGES AND ACTIVATION OF AKT/GSK3 SIGNALING IN OVINE CLN6 NEURONAL CEROID LIPOFUSCINOSIS.

Mutations in the CLN6 gene Cotton Socks cause a variant late infantile form of neuronal ceroid lipofuscinosis (NCL; Batten disease).CLN6 loss leads to disease clinically characterized by vision impairment, motor and cognitive dysfunction, and seizures.Accumulating evidence suggests that alterations in metal homeostasis and cellular signaling pathwa

IL-17 is a cytokine produced by innate and acquired immunity cells that have an action against fungi and bacteria.However, its action in helminth infections is unclear, including in Toxocara canis infection.Toxocariasis is a neglected zoonosis representing a significant public health problem with an estimated seroprevalence of 19% Body worldwide.In

Cognition is very important in our daily life.However, amblyopia has abnormal visual cognition.Physiological changes of the brain during processes of cognition could be reflected with ERPs.So the purpose of this study was to investigate the speed and the capacity of resource allocation in visual cognitive processing in orientation discrimination ta

Background: Self help groups provide a critical outlet for building more sustainable socioeconomic status.They have emerged as support groups in facing all kinds of problems in their domestic environment and makes a significant impact on their socio economic status and empowerment.Objectives: The objectives of the study was to study the socio demog